Article
Association of the RGS2 gene with extrapyramidal symptoms induced by treatment with antipsychotic medication.
Pharmacogenetics and genomics - 1 Jul 2007
Greenbaum Lior, Strous Rael D, Kanyas Kyra, Merbl Yifat, Horowitz Anat, Karni Osnat, Katz Elena, Kotler Moshe, Olender Tsviya, Deshpande Smita N, Lancet Doron, Ben-Asher Edna, Lerer Bernard
Abstract excerpt
OBJECTIVES: To investigate the role of genes encoding regulators of G protein signaling in early therapeutic response to antipsychotic drugs and in susceptibility to drug-induced extrapyramidal symptoms. As regulators of G protein signaling and regulators of G protein signaling-like proteins play a pivotal role in dopamine receptor signaling, genetically based, functional variation could contribute to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
