Microsatellite instability in poorly differentiated adenocarcinomas of the colon and rectum: relationship to clinicopathological features

Abstract excerpt

BACKGROUND: Poorly differentiated adenocarcinomas of the colon and rectum (Por) feature the worst prognosis among the various types of colorectal carcinomas. Por is highly associated with microsatellite instability (MSI), although MSI is associated with an improved prognosis in colorectal cancers. AIM: To investigate the influence of MSI on clinicopathological features and survival of patients affected by Por....

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