Article
Unaffected family members and schizophrenia patients share brain structure patterns: a high-dimensional pattern classification study.
Biological psychiatry - 1 Jan 2008
Fan Yong, Gur Raquel E, Gur Ruben C, Wu Xiaoying, Shen Dinggang, Calkins Monica E, Davatzikos Christos
Abstract excerpt
BACKGROUND: A number of studies have provided evidence for genetic modulation of brain structure in unaffected family members (FM) of schizophrenia patients using conventional volumetric analysis. High-dimensional pattern classification methods have been reported to have the capacity to determine subtle and spatially complex structural patterns that distinguish schizophrenia patients from healthy control subjects...
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