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Article

Multivariate pattern analysis reveals subtle brain anomalies relevant to the cognitive phenotype in neurofibromatosis type 1.

Human brain mapping - 1 Jan 2014

Duarte João V, Ribeiro Maria J, Violante Inês R, Cunha Gil, Silva Eduardo, Castelo-Branco Miguel

Abstract excerpt

Neurofibromatosis Type 1 (NF1) is a common genetic condition associated with cognitive dysfunction. However, the pathophysiology of the NF1 cognitive deficits is not well understood. Abnormal brain structure, including increased total brain volume, white matter (WM) and grey matter (GM) abnormalities have been reported in the NF1 brain. These previous studies employed univariate model-driven methods preventing...

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Identifiers

PMID: 22965669
DOI: 10.1002/hbm.22161
PMCID: PMC6869472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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