Article
Structural brain abnormalities among relatives of patients with schizophrenia: implications for linkage studies.
Schizophrenia research - 1 Apr 2003
Faraone Stephen V, Seidman Larry J, Kremen William S, Kennedy David, Makris Nikos, Caviness Verne S, Goldstein Jill, Tsuang Ming T
Abstract excerpt
Several studies suggest that the nonschizophrenic relatives of schizophrenic patients exhibit structural brain abnormalities that may be manifestations of genes that predispose to schizophrenia. In this work, we examine the utility of such measures for linkage analyses. Subjects were 45 nonpsychotic first-degree adult relatives of schizophrenic patients and 48 normal controls. Sixty contiguous 3-mm coronal,...
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