Article
The dysbindin gene (DTNBP1) is associated with methamphetamine psychosis.
Biological psychiatry - 15 Jan 2008
Kishimoto Makiko, Ujike Hiroshi, Motohashi Yasuko, Tanaka Yuji, Okahisa Yuko, Kotaka Tatsuya, Harano Mutsuo, Inada Toshiya, Yamada Mitsuhiko, Komiyama Tokutaro, Hori Toru, Sekine Yoshimoto, Iwata Nakao, Sora Ichiro, Iyo Masaomi, Ozaki Norio, Kuroda Shigetoshi
Abstract excerpt
BACKGROUND: The dysbindin (DTNBP1 [dystrobrevin-binding protein 1]) gene has repeatedly been shown to be associated with schizophrenia across diverse populations. One study also showed that risk haplotypes were shared with a bipolar disorder subgroup with psychotic episodes, but not with all cases. DTNBP1 may confer susceptibility to psychotic symptoms in various psychiatric disorders besides schizophrenia....
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