Article
A polymorphism in the dysbindin gene (DTNBP1) associated with multiple psychiatric disorders including schizophrenia.
Behavioral and brain functions : BBF - 9 Jul 2010
Voisey Joanne, Swagell Christopher D, Hughes Ian P, Connor Jason P, Lawford Bruce R, Young Ross M, Morris C Phillip
Abstract excerpt
BACKGROUND: A number of studies have found associations between dysbindin (DTNBP1) polymorphisms and schizophrenia. Recently we identified a DTNBP1 SNP (rs9370822) that is strongly associated with schizophrenia. Individuals diagnosed with schizophrenia were nearly three times as likely to carry the CC genotype compared to the AA genotype. METHODS: To investigate the importance of this SNP in the function of...
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