Article
Association of the DTNBP1 locus with schizophrenia in a U.S. population.
American journal of human genetics - 1 Nov 2004
Funke Birgit, Finn Christine T, Plocik Alex M, Lake Stephen, DeRosse Pamela, Kane John M, Kucherlapati Raju, Malhotra Anil K
Abstract excerpt
Linkage and association studies have recently implicated dystrobrevin-binding protein 1 (DTNBP1) in the etiology of schizophrenia. We analyzed seven previously tested DTNBP1 single-nucleotide polymorphisms (SNPs) in a cohort of 524 individuals with schizophrenia or schizoaffective disorder and 573 control subjects. The minor alleles of three SNPs (P1578, P1763, and P1765) were positively associated with the...
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