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Article

Experimental and analytical variation in human urine in 1H NMR spectroscopy-based metabolic phenotyping studies.

Analytical chemistry - 15 Jul 2007

Maher Anthony D, Zirah Séverine F M, Holmes Elaine, Nicholson Jeremy K

Abstract excerpt

1H NMR spectroscopy potentially provides a robust approach for high-throughput metabolic screening of biofluids such as urine and plasma, but sample handling and preparation need careful optimization to ensure that spectra accurately report biological status or disease state. We have investigated the effects of storage temperature and time on the 1H NMR spectral profiles of human urine from two participants,...

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PMID: 17555297
DOI: 10.1021/ac070212f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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