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Article

Assessment of analytical reproducibility of 1H NMR spectroscopy based metabonomics for large-scale epidemiological research: the INTERMAP Study.

Analytical chemistry - 1 Apr 2006

Dumas Marc-Emmanuel, Maibaum Elaine C, Teague Claire, Ueshima Hirotsugu, Zhou Beifan, Lindon John C, Nicholson Jeremy K, Stamler Jeremiah, Elliott Paul, Chan Queenie, Holmes Elaine

Abstract excerpt

Large-scale population phenotyping for molecular epidemiological studies is subject to all the usual criteria of analytical chemistry. As part of a major phenotyping investigation we have used high-resolution 1H NMR spectroscopy to characterize 24-h urine specimens obtained from population samples in Aito Town, Japan (n = 259), Chicago, IL (n = 315), and Guangxi, China (n = 278). We have investigated analytical...

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PMID: 16579598
DOI: 10.1021/ac0517085
PMCID: PMC6561113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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