Article
Human metabolic phenotype diversity and its association with diet and blood pressure.
Nature - 15 May 2008
Holmes Elaine, Loo Ruey Leng, Stamler Jeremiah, Bictash Magda, Yap Ivan K S, Chan Queenie, Ebbels Tim, De Iorio Maria, Brown Ian J, Veselkov Kirill A, Daviglus Martha L, Kesteloot Hugo, Ueshima Hirotsugu, Zhao Liancheng, Nicholson Jeremy K, Elliott Paul
Abstract excerpt
Metabolic phenotypes are the products of interactions among a variety of factors-dietary, other lifestyle/environmental, gut microbial and genetic. We use a large-scale exploratory analytical approach to investigate metabolic phenotype variation across and within four human populations, based on 1H NMR spectroscopy. Metabolites discriminating across populations are then linked to data for individuals on blood...
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