Article
Positional pathway screen of wnt signaling genes in schizophrenia: association with DKK4.
Biological psychiatry - 1 Jan 2008
Proitsi Petroula, Li Tao, Hamilton Gillian, Di Forti Marta, Collier David, Killick Richard, Chen Ronald, Sham Pak, Murray Robin, Powell John, Lovestone Simon
Abstract excerpt
BACKGROUND: Wnt signaling has been implicated in schizophrenia from studies of gene expression in patients, from an understanding of the function of reported susceptibility genes and from experimental studies of psychoactive drugs. This diverse evidence suggests that wnt signaling genes, defined as pathway participants, modifiers or targets, are good candidates as susceptibility factors. METHODS: We performed a...
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