Article
Pharmacogenetically hazardous drugs: a proposed new scoring method.
Acta physiologica Hungarica - 1 Jan 1991
Szórády I, Sánta A
Abstract excerpt
Similar doses of a drug given to different individuals can result in widely disparate plasma concentrations and hence effects. Beside intraindividual differences also inter-ethnic differences of drug response must be taken into consideration. Both inter-individual and inter-ethnic variations of drug response are mostly related to genetic factors (polymorphism) involved in drug metabolism and kinetics. The...
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