Article
Toxicogenetics in drug development.
Toxicology letters - 31 Mar 2001
Park B K, Pirmohamed M
Abstract excerpt
The major progress made in the understanding of the genetic basis of inter-individual variation in drug response, alongside the rapid advances in technology, provides major new opportunities to ensure the safe introduction of a new chemical entity into clinical practice. In essence, the aim is to get the right drug into the right patient using knowledge of factors that influence both benefit and risk. The stage...
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