Article
Genetic cause of autosomal recessive hereditary nephropathy in the English Cocker Spaniel.
Journal of veterinary internal medicine - 1 Jan 2000
Davidson Ashley G, Bell Rebecca J, Lees George E, Kashtan Clifford E, Davidson George S, Murphy Keith E
Abstract excerpt
BACKGROUND: Autosomal recessive hereditary nephropathy (ARHN) in the English Cocker Spaniel is caused by a type IV collagen defect, but the underlying mutation is unknown. ANIMALS: One hundred thirty-four English Cocker Spaniels (12 with ARHN, 8 obligate carriers, and 114 others), 3 mixed breed dogs with X-linked hereditary nephropathy (XLHN), and 7 other dogs without hereditary nephropathy were included....
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