Article
Small RNA sequencing evaluation of renal microRNA biomarkers in dogs with X-linked hereditary nephropathy.
Scientific reports - 31 Aug 2021
Chu Candice P, Liu Shiguang, Song Wenping, Xu Ethan Y, Nabity Mary B
Abstract excerpt
Dogs with X-linked hereditary nephropathy (XLHN) are an animal model for Alport syndrome in humans and progressive chronic kidney disease (CKD). Using mRNA sequencing (mRNA-seq), we have characterized the gene expression profile affecting the progression of XLHN; however, the microRNA (miRNA, miR) expression remains unknown. With small RNA-seq and quantitative RT-PCR (qRT-PCR), we used 3 small RNA-seq analysis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.