Article
Characterization of the genetic basis for autosomal recessive hereditary nephropathy in the English Springer Spaniel.
Journal of veterinary internal medicine - 1 Jan 2000
Nowend K L, Starr-Moss A N, Lees G E, Berridge B R, Clubb F J, Kashtan C E, Nabity M B, Murphy K E
Abstract excerpt
BACKGROUND: Autosomal recessive hereditary nephropathy (ARHN) was diagnosed in 2 English Springer Spaniels (ESS), a breed not previously reported to be affected by hereditary nephropathy (HN). OBJECTIVE: To identify and characterize the genetic cause of ARHN in ESS. ANIMALS: Sixty-three ESS (2 with ARHN, 2 obligate carriers, and 59 others), 2 mixed-breed dogs with X-linked HN, and 2 English Cocker Spaniels (ECS)...
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