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Article

ANLN truncation causes a familial fatal acute respiratory distress syndrome in Dalmatian dogs.

PLoS genetics - 1 Feb 2017

Holopainen Saila, Hytönen Marjo K, Syrjä Pernilla, Arumilli Meharji, Järvinen Anna-Kaisa, Rajamäki Minna, Lohi Hannes

Abstract excerpt

Acute respiratory distress syndrome (ARDS) is the leading cause of death in critical care medicine. The syndrome is typified by an exaggerated inflammatory response within the lungs. ARDS has been reported in many species, including dogs. We have previously reported a fatal familial juvenile respiratory disease accompanied by occasional unilateral renal aplasia and hydrocephalus, in Dalmatian dogs. The condition...

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Source

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Identifiers

PMID: 28222102
DOI: 10.1371/journal.pgen.1006625
PMCID: PMC5340406

Genes

ANLN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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