Article
Reduced membrane protein methylation in red cells of the McLeod blood group phenotype.
Transfusion - 1 Jan 2000
Wainfan E, Kilkenny M, Johnson C, Marsh W L
Abstract excerpt
Red cells (RBCs) contain an abundance of protein methylase II, which catalyzes the transfer of methyl groups from S-adenosylmethionine to carboxyl groups of aspartyl and glutamyl residues in proteins. Enzyme-catalyzed transfer of methyl groups, labeled with 14C or 3H, from S-adenosylmethionine to membrane proteins of McLeod, Ko, and control RBCs was assayed by determining the acceptance of labeled methyl groups...
Topics
- Erythrocyte Membrane
- Humans
- Kell Blood-Group System
- Male
- Membrane Proteins
- Methylation
- Phenotype