Article
The role of pfmdr1 in Plasmodium falciparum tolerance to artemether-lumefantrine in Africa.
Tropical medicine & international health : TM & IH - 1 Jun 2007
Sisowath Christin, Ferreira Pedro E, Bustamante Leyla Y, Dahlström Sabina, Mårtensson Andreas, Björkman Anders, Krishna Sanjeev, Gil José P
Abstract excerpt
OBJECTIVE: Artemether-lumefantrine (AL), presently the most favoured combination therapy against uncomplicated Plasmodium falciparum malaria in Africa, has recently shown to select for the pfmdr1 86N allele. The objective of this study was to search for the selection of other mutations potentiall...
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