Article
Immunologically relevant strain polymorphism in the Amastigote Surface Protein 2 of Trypanosoma cruzi.
Microbes and infection - 1 Jul 2007
Claser Carla, Espíndola Noeli Maria, Sasso Gisela, Vaz Adelaide José, Boscardin Silvia B, Rodrigues Mauricio M
Abstract excerpt
Several evidences suggest that the Amastigote Surface Protein-2 (ASP-2) of Trypanosoma cruzi is an important target for immunity during infection. Based on this, we considered it important to evaluate its strain polymorphism. Initially, we observed the presence of conserved cross-reactive epitopes in amastigotes of all parasite strains tested. In addition, the predicted amino acid sequences of the genes isolated...
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