Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cloning and sequence analysis of the TcP2 beta cDNA variants of Trypanosoma cruzi.

Biochimica et biophysica acta - 17 Oct 1995

Schijman A G, Vazquez M P, Dov C B, Ghio S, Lorenzi H, Levin M J

Abstract excerpt

P2 beta acidic ribosomal protein is a relevant antigen in Chagas' disease. cDNA cloning demonstrated that Trypanosoma cruzi expresses at least six types of TcP2 beta transcripts that differed by point nucleotides substitutions. The distribution and type of mutations seemed to follow the typical structural organization of eukaryotic acidic ribosomal proteins. Most of the synonymous changes clustered in the...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
DNA, Complementary
Molecular Sequence Data
Mutation
Ribosomal Proteins
Sequence Alignment
Trypanosoma cruzi

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7578249
DOI: 10.1016/0167-4781(95)00142-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7578249-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cloning and sequence analysis of the TcP2 beta cDNA variants of Trypanosoma cruzi.PMID 7578249Read ↗

Genomic organization and expression profile of the mucin-associated surface protein (masp) family of the human pathogen Trypanosoma cruziSemantic proximity Read ↗

The trypanosome Variant Surface Glycoprotein mRNA is stabilized by an essential unconventional RNA-binding proteinSemantic proximity Read ↗

Functional insights from a surface antigen mRNA-bound proteomeSemantic proximity Read ↗

The Trypanosoma cruzi mucin family is transcribed from hundreds of genes having hypervariable regions.Semantic proximity Read ↗

Trypanosoma cruzi ribosomal protein S4: characterization of its coding locus, analysis of transcripts, and antigenicity of the protein.Semantic proximity Read ↗

Differential accumulation of mutations localized in particular domains of the mucin genes expressed in the vertebrate host stage of Trypanosoma cruzi.Semantic proximity Read ↗

A sequence previously identified as metastasis-related encodes an acidic ribosomal phosphoprotein, P2Semantic proximity Read ↗

A high-throughput cloning system for reverse genetics in Trypanosoma cruziSemantic proximity Read ↗

Trypanosoma cruzi: allelic comparisons of the actin genes and analysis of their transcripts.Semantic proximity Read ↗

Immunologically relevant strain polymorphism in the Amastigote Surface Protein 2 of Trypanosoma cruzi.Semantic proximity Read ↗

Antigenic diversity of MASP gene family of Trypanosoma cruziSemantic proximity Read ↗

Alternative splicing within and between alleles of the ATPase gene 1 locus of Trypanosoma brucei.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.