Article
The toll-like receptor 4 Asp299Gly variant and tuberculosis susceptibility in HIV-infected patients in Tanzania.
AIDS (London, England) - 19 Jun 2007
Ferwerda Bart, Kibiki Gibson S, Netea Mihai G, Dolmans Wil M V, van der Ven Andre J
Abstract excerpt
Toll-like receptor 4 (TLR4) plays an important role in the pattern recognition of Mycobacterium tuberculosis, and polymorphisms in the TLR4 gene influence the function of the receptor. We therefore investigated in a cohort of HIV-infected Tanzanian patients whether the Asp299Gly TLR4 polymorphism...
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