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Article

Single Nucleotide Polymorphisms in TLR4 Affect Susceptibility to Tuberculosis in Mexican Population from the State of Veracruz.

Journal of immunology research - 1 Jan 2020

Ortega Enrique, Hernández-Bazán Sujhey, Sánchez-Hernández Beatriz, Licona-Limón Ileana, Fuentes-Dominguez Javier

Abstract excerpt

Tuberculosis is still a global public health problem, with an estimated 10 million new cases and 1.6 million deaths in 2017. Of all humans infected with M. tuberculosis, only 10-15% will develop active tuberculosis disease during their lifetime, and data suggest that along with environmental factors, genetic factors influence susceptibility to develop active disease. Toll-like receptors (TLRs) are pattern...

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Identifiers

PMID: 32411792
DOI: 10.1155/2020/2965697
PMCID: PMC7204096

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