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Article

Kallikrein 4 Is a Proliferative Factor that Is Overexpressed in Prostate Cancer

1 Jun 2007

Abstract excerpt

Kallikrein 4 (KLK4) is a member of the human tissue KLK family. Whereas all other KLKs are secreted proteins with extracellular functions, KLK4 is primarily localized to the nucleus, indicating that it has a different function compared with other members of the KLK family. In addition, KLK4 expression is highly enriched in the prostate and is regulated by androgens. Here, we studied the possible functional role...

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PMID: 17545602
DOI: 10.1158/0008-5472.can-06-4728

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