Article
Matrix metalloproteinase-3 and coronary remodelling: implications for unstable coronary disease.
Cardiovascular research - 1 Sept 2007
White Anthony J, Duffy Stephen J, Walton Anthony S, Ng Jer Fuu, Rice Gregory E, Mukherjee Swati, Shaw James A, Jennings Garry L, Dart Anthony M, Kingwell Bronwyn A
Abstract excerpt
OBJECTIVES: Matrix metalloproteinases (MMPs) are plausible candidates for prediction of unstable coronary syndromes. We hypothesised that the MMP-3 polymorphism (- 1171, 5A/6A) would relate to coronary plaque characteristics and unstable clinical presentation. METHODS AND RESULTS: Forty patients with de novo presentation of coronary artery disease (CAD) were classified into unstable coronary syndrome (n=19) or...
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