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Article

Update on new GH-IGF axis genetic defects.

Archives of endocrinology and metabolism - 1 Jan 2000

Vasques Gabriela A, Andrade Nathalia L M, Correa Fernanda A, Jorge Alexander A L

Abstract excerpt

The somatotropic axis is the main hormonal regulator of growth. Growth hormone (GH), also known as somatotropin, and insulin-like growth factor 1 (IGF-1) are the key components of the somatotropic axis. This axis has been studied for a long time and the knowledge of how some molecules could promote or impair hormones production and action has been growing over the last decade. The enhancement of large-scale...

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Identifiers

PMID: 31939486
DOI: 10.20945/2359-3997000000191
PMCID: PMC10522240

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Source receipt: pubmed, retrieved 7 Sept 2026.

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