Growth disorders caused by genetic defects in the growth hormone pathway.

Article

Growth disorders caused by genetic defects in the growth hormone pathway.

Advances in pediatrics - 1 Jan 1998

Cogan J D, Phillips J A

Abstract excerpt

The growth hormone (GH) pathway is composed of a series of interdependent genes whose products are required for normal growth (Fig 1). The GH pathway genes include ligands (GH and insulin-like growth factor 1 [lGF-1]), transcription factors (prophet of pit 1, or prop 1 and pit 1), agonists and an...

Topics

Growth Disorders
Growth Hormone-Releasing Hormone
Human Growth Hormone
Humans
Mutation
Receptors, Neuropeptide
Receptors, Pituitary Hormone-Regulating Hormone
Syndrome

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