Article

Insight into the Role and Regulation of Gap Junction Genes in Lung Cancer and Identification of Nuclear Cx43 as a Putative Biomarker of Poor Prognosis

2019-02-13

Abstract excerpt

Direct intercellular communication, mediated by gap junctions formed by the connexin transmembrane protein family, is frequently dysregulated in cancer. Connexins have been described as tumour suppressors, but emerging evidence suggests that they can also act as tumour promoters. This feature is connexin- and tissue-specific and may be mediated by complex signalling pathways through gap junctions or hemichannels o...

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Literature Corpus work: 938ce6f1-5c70-5ab9-8ed7-f1ebc86ea895
DOI: 10.20944/preprints201902.0109.v1

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