Adrenalectomy in the Zucker fatty rat: effect on m-RNA for malic enzyme and glyceraldehyde 3-phosphate dehydrogenase.

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Article

Adrenalectomy in the Zucker fatty rat: effect on m-RNA for malic enzyme and glyceraldehyde 3-phosphate dehydrogenase.

International journal of obesity - 1 Oct 1991

Bray G A, York D A, Lavau M, Hainault I

Abstract excerpt

The effects of adrenalectomy with or without replacement doses of corticosterone were examined on the levels of messenger RNA for malic enzyme (ME) and glyceraldehyde 3-phosphate dehydrogenase (GAPDH) in adipose tissue and liver from Zucker fatty (fa/fa) and littermate lean rats. The levels of both GAPDH and ME mRNAs were increased in the obese rats. Adrenalectomy markedly reduced the m-RNA for GAPDH and ME in...

Topics

Adipose Tissue
Adrenal Glands
Adrenalectomy
Animals
Body Weight
Corticosterone
Densitometry
Dose-Response Relationship, Drug
Female
Genotype
Glyceraldehyde-3-Phosphate Dehydrogenases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver

Malate Dehydrogenase

Male

Obesity

RNA, Messenger

Rats

Rats, Zucker

Source

Open in PubMed

Identifiers

PMID: 1752731

Genes

GAPDH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1752731-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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