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Article

Direct and indirect effects of growth hormone receptor ablation on liver expression of xenobiotic metabolizing genes.

American journal of physiology. Endocrinology and metabolism - 15 Oct 2013

Li Xinna, Bartke Andrzej, Berryman Darlene E, Funk Kevin, Kopchick John J, List Edward O, Sun Liou, Miller Richard A

Abstract excerpt

Detoxification of ingested xenobiotic chemicals, and of potentially toxic endogenous metabolites, is carried out largely through a series of enzymes synthesized in the liver, sometimes called "xenobiotic metabolizing enzymes" (XME). Expression of these XME is sexually dimorphic in rodents and humans, with many of the XME expressed at higher levels in females. This expression pattern is thought to be regulated, in...

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Identifiers

PMID: 23941873
DOI: 10.1152/ajpendo.00304.2013
PMCID: PMC3798695

Genes

GHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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