Article
Gene expression of lipid storage-related enzymes in adipose tissue of the genetically obese Zucker rat. Co-ordinated increase in transcriptional activity and potentiation by hyperinsulinaemia.
The Biochemical journal - 1 Feb 1992
Dugail I, Quignard-Boulangé A, Le Liepvre X, Ardouin B, Lavau M
Abstract excerpt
The genetically obese Zucker rat displays excessive fat storage capacity which is due to a tissue-specific increase in the activities of a number of lipid storage-related enzymes in adipose tissue. The aim of this study was to investigate the molecular mechanism responsible for this phenomenon. L...
Topics
- Adipose Tissue
- Aging
- Animals
- Blotting, Northern
- Gene Expression
- Genotype
- Glyceraldehyde-3-Phosphate Dehydrogenases
- Glycerolphosphate Dehydrogenase
- Insulin
- Lipid Metabolism
- Lipoprotein Lipase
- Malate Dehydrogenase
- Nucleic Acid Hybridization
- Obesity