Article
Contribution of Atg1-dependent autophagy to TOR-mediated cell growth and survival.
Autophagy - 1 Jan 2000
Neufeld Thomas P
Abstract excerpt
The Ser/Thr kinase Atg1 (Ulk1/Unc51) appears to act as a convergence point for multiple signals that regulate autophagy, and in turn interacts with a large number of autophagy-related (Atg) proteins. Working in the Drosophila system, we recently found that overexpression of Atg1 is sufficient to induce autophagy, independent of upstream nutrient signals. We exploited this finding to examine the roles of autophagy...
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