Article
Genetic disorders of vision revealed by a behavioral screen of 400 essential loci in zebrafish.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Oct 1999
Neuhauss S C, Biehlmaier O, Seeliger M W, Das T, Kohler K, Harris W A, Baier H
Abstract excerpt
We examined optokinetic and optomotor responses of 450 zebrafish mutants, which were isolated previously based on defects in organ formation, tissue patterning, pigmentation, axon guidance, or other visible phenotypes. These strains carry single point mutations in >400 essential loci. We asked which fraction of the mutants develop blindness or other types of impairments specific to the visual system. Twelve...
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