Article
A behavioral screen for isolating zebrafish mutants with visual system defects.
Proceedings of the National Academy of Sciences of the United States of America - 7 Nov 1995
Brockerhoff S E, Hurley J B, Janssen-Bienhold U, Neuhauss S C, Driever W, Dowling J E
Abstract excerpt
Optokinetic and phototactic behaviors of zebrafish larvae were examined for their usefulness in screening for recessive defects in the visual system. The optokinetic response can be reliably and rapidly detected in 5-day larvae, whereas the phototactic response of larvae is variable and not robus...
Topics
- Animals
- Behavior, Animal
- Crosses, Genetic
- Electroretinography
- Ethylnitrosourea
- Eye
- Eye Abnormalities
- Genes, Recessive
- Larva
- Light
- Mutagenesis
- Mutation
- Nystagmus, Optokinetic
- Optic Nerve
- Retina
- Selection, Genetic
- Zebrafish