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Article

Polymorphisms in TRAIL receptor genes and risk of breast cancer in Spanish women.

Cancer biomarkers : section A of Disease markers - 1 Jan 2007

Martinez-Ferrandis José I, Rodríguez-López Raquel, Milne Roger L, González Emilio, Cebolla Elvira, Chirivella Isabel, Zamora Pilar, Arias José I, Palacios Santiago, Cervantes Andrés, Díez Orland, Benitez Javier, Armengod M-Eugenia

Abstract excerpt

TRAIL is a potent inducer of apoptosis in malignant but not in normal cells. TRAIL binds to the proapoptotic death receptor DR4 and DR5 as well as to the decoy receptors DcR1 and DcR2. To evaluate the involvement of TRAIL receptor genes in breast cancer, we carried out a case-control study of eight selected polymorphisms in a large sample of Spanish women. Three of the eight selected SNPs (626G/C and 1322G/A in...

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Identifiers

PMID: 17522430
DOI: 10.3233/cbm-2007-3203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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