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Article

Renin-angiotensin system haplotypes and the risk of myocardial infarction and stroke in pharmacologically treated hypertensive patients.

American journal of epidemiology - 1 Jul 2007

Marciante Kristin D, Bis Joshua C, Rieder Mark J, Reiner Alexander P, Lumley Thomas, Monks Stephanie A, Kooperberg Charles, Carlson Christopher, Heckbert Susan R, Psaty Bruce M

Abstract excerpt

The products of the renin-angiotensin system (RAS) play an important role in the pathogenesis of cardiovascular disease. Studies examining RAS gene variants and cardiovascular disease have focused on single-nucleotide polymorphisms (SNPs) rather than haplotypes, which better characterize the patterns of genetic variation. The authors conducted a population-based, case-control study at Group Health (Seattle,...

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Source

Identifiers

PMID: 17522061
DOI: 10.1093/aje/kwm059

Genes

AGT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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