Article
Angiotensin II type I receptor gene and myocardial infarction: tagging SNPs and haplotype based association study. The Beijing atherosclerosis study.
Pharmacogenetics - 1 Oct 2004
Su Shaoyong, Chen Jianhong, Zhao Jiangong, Huang Jianfeng, Wang Xiaoling, Chen Runsheng, Gu Dongfeng
Abstract excerpt
OBJECTIVES: The present study aimed to assess the effect of haplotype variation in angiotensin II type I receptor (AGTR1) gene on the risk of myocardial infarction (MI) in Chinese males. METHODS: We used 48 patients to identify the putative functional polymorphisms in AGTR1 gene by direct sequencing. The program tagSNPs was used to identify an optimal set of tagging single nucleotide polymorphisms (SNPs). These...
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