Article
Angiotensinogen single nucleotide polymorphisms, elevated blood pressure, and risk of cardiovascular disease.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 2003
Sethi Amar A, Nordestgaard Børge G, Grønholdt Marie-Louise M, Steffensen Rolf, Jensen Gorm, Tybjaerg-Hansen Anne
Abstract excerpt
In this study of 10 690 individuals, associations with elevated blood pressure, ischemic heart disease, and ischemic cerebrovascular disease were determined for two noncoding [A(-20)C, G(-6)A] and two coding (T174M, M235T) single nucleotide polymorphisms, analyzed alone and in combination (haplotypes). Participants from the general population with (n=4950) and without (n=4234) elevated blood pressure were...
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