Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resistance Exercise Reverses Aging in Human Skeletal Muscle

23 May 2007

Abstract excerpt

Human aging is associated with skeletal muscle atrophy and functional impairment (sarcopenia). Multiple lines of evidence suggest that mitochondrial dysfunction is a major contributor to sarcopenia. We evaluated whether healthy aging was associated with a transcriptional profile reflecting mitochondrial impairment and whether resistance exercise could reverse this signature to that approximating a younger...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mitochondrial Function and Pathology
Share to Muscle Physiology and Disorders
Share to Nutrition and Health in Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17520024
DOI: 10.1371/journal.pone.0000465

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance Exercise Reverses Aging in Human Skeletal MusclePMID 17520024Read ↗

Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscleSemantic proximity Read ↗

Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscleSemantic proximity Read ↗

Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adultsSemantic proximity Read ↗

Differential genomic responses in old vs. young humans despite similar levels of modest muscle damage after resistance loadingSemantic proximity Read ↗

Transcriptomic meta‐analysis of disuse muscle atrophy vs. resistance exercise‐induced hypertrophy in young and older humansSemantic proximity Read ↗

Metformin alters skeletal muscle transcriptome adaptations to resistance training in older adultsSemantic proximity Read ↗

Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscleSemantic proximity Read ↗

Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and species-specific changesSemantic proximity Read ↗

Unravelling the Transcriptomic Symphony of Sarcopenia: Key Pathways and Hub Genes Altered by Muscle Ageing and Caloric Restriction Revealed by RNA SequencingSemantic proximity Read ↗

MYORG and STRADB as Activity-Dependent Therapeutic Targets for Frailty Prevention: Discovery and Cross-Cohort Validation in Aging Skeletal MuscleSemantic proximity Read ↗

Cellular and Molecular Basis of Age-Related SarcopeniaSemantic proximity Read ↗

Age-related changes in human skeletal muscle transcriptome and proteome are more affected by chronic inflammation and physical inactivity than primary agingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.