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Article

Association of osteopontin gene haplotypes with nephrolithiasis.

Kidney international - 1 Sept 2007

Gao B, Yasui T, Itoh Y, Li Z, Okada A, Tozawa K, Hayashi Y, Kohri K

Abstract excerpt

Osteopontin (OPN) is one of the glycosylated phosphoproteins produced in the kidney that can modulate nephrolithiasis. We had previously found a modest association between OPN gene polymorphisms and the risk for urinary stone formation. In order to determine if sequence variants within the OPN gene could be linked to the risk of nephrolithiasis; we sequenced the entire OPN gene of 45 stone forming patients and 54...

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Identifiers

PMID: 17519954
DOI: 10.1038/sj.ki.5002345

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