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Article

Osteopontin promoter polymorphisms and risk of urolithiasis: a candidate gene association and meta-analysis study.

BMC medical genetics - 25 Aug 2020

Amar Ali, Afzal Ayesha, Hameed Athar, Ahmad Mumtaz, Khan Abdul Rafay, Najma Humaira, Abid Aiysha, Khaliq Shagufta

Abstract excerpt

BACKGROUND: Urolithiasis is a worldwide urological problem with significant contribution of genetic factors. Pakistan, which resides within the Afro-Asian stone belt, has a high reported prevalence (12%) of urolithiasis. Osteopontin (SPP1) is a urinary macromolecule with a suggested critical role in modulating renal stone formation, genetic polymorphisms of which may determine individual risk of developing...

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Identifiers

PMID: 32842990
DOI: 10.1186/s12881-020-01101-2
PMCID: PMC7446165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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