Article
A polymorphism of the osteopontin gene is related to urinary calcium stones.
The Journal of urology - 1 Oct 2005
Gao Bing, Yasui Takahiro, Okada Atsushi, Tozawa Keiichi, Hayashi Yutaro, Kohri Kenjiro
Abstract excerpt
PURPOSE: We investigated polymorphisms of the osteopontin (OPN) gene to explore whether they could be used as a gene marker for determining the risk of urinary calcium stones. MATERIALS AND METHODS: A total of 76 patients with urinary calcium stones and 124 controls were studied. Two single nucleotide polymorphisms with nonsynonymous amino acid located at positions 9,402 (Arg/His) and 9,171 (Asn/Ser) in the OPN...
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