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Article

Association between the T-593A and C6982T polymorphisms of the osteopontin gene and risk of developing nephrolithiasis.

Archives of medical research - 1 Aug 2010

Gögebakan Bülent, Igci Yusuf Ziya, Arslan Ahmet, Igci Mehri, Erturhan Sakıp, Oztuzcu Serdar, Sen Haluk, Demiryürek Seniz, Arikoglu Hilal, Cengiz Beyhan, Bayraktar Recep, Yurtseven Cihanser, Sarıca Kemal, Demiryürek Abdullah T

Abstract excerpt

BACKGROUND AND AIMS: Increased synthesis of several urinary proteins including osteopontin (OPN) has been shown to be associated with stone formation within the urinary tract. The objective of this study was to analyze the genotype distributions and allele frequencies for OPN gene promoter T-593A and C6982T (in exon 7) polymorphisms among patients with kidney stones. METHODS: In this case-control study, the study...

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PMID: 21044748
DOI: 10.1016/j.arcmed.2010.08.014

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