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Article

Genetic screen of a mutant poxvirus library identifies an ankyrin repeat protein involved in blocking induction of avian type I interferon.

Journal of virology - 1 May 2013

Laidlaw Stephen M, Robey Rebecca, Davies Marc, Giotis Efstathios S, Ross Craig, Buttigieg Karen, Goodbourn Stephen, Skinner Michael A

Abstract excerpt

Mammalian poxviruses, including vaccinia virus (VACV), have evolved multiple mechanisms to evade the host type I interferon (IFN) responses at different levels, with viral proteins targeting IFN induction, signaling, and antiviral effector functions. Avian poxviruses (avipoxviruses), which have been developed as recombinant vaccine vectors for permissive (i.e., poultry) and nonpermissive (i.e., mammals, including...

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Identifiers

PMID: 23427153
DOI: 10.1128/JVI.02736-12
PMCID: PMC3624286

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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