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Article

Recurring Translocation (10;17) and Deletion (14q) in Clear Cell Sarcoma of the Kidney

1 Mar 2007

Abstract excerpt

Abstract Context.—Clear cell sarcoma of the kidney (CCSK) is a prognostically unfavorable renal neoplasm of childhood. Previous cytogenetic studies of CCSK have reported balanced translocations t(10;17)(q22;p13) and t(10;17)(q11; p12). Although the tumor suppressor gene p53 is located at the chromosome 17p13 breakpoint, p53 abnormalities are rarely present in these tumors. Objective.—To identify cytogenetic...

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Identifiers

PMID: 17516747
DOI: 10.5858/2007-131-446-rtadqi

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