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Article

Mutation in G6PD gene leads to loss of cellular control of protein glutathionylation: mechanism and implication.

Journal of cellular biochemistry - 1 Jan 2008

Ayene Iraimoudi S, Biaglow John E, Kachur Alexander V, Stamato Thomas D, Koch Cameron J

Abstract excerpt

More than 400 million people are susceptible to oxidative stress due to glucose-6-phosphate dehydrogenase (G6PD) deficiency. Protein glutathionylation is believed to be responsible for loss of protein function and/or cellular signaling during oxidative stress. To elucidate the implications of G6PD deficiency specifically in cellular control of protein glutathionylation, we used hydroxyethyldisulfide (HEDS), an...

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PMID: 17516514
DOI: 10.1002/jcb.21394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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