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Article

[Molecular basics of Alzheimer's disease].

Molekuliarnaia biologiia - 1 Jan 2000

Grigorenko A P, Rogaev E I

Abstract excerpt

Studies of molecular mechanisms for Alzheimer's Disease have led to the two major achievements. First, genes with mutations causing Alzheimer's Disease (presenilin genes PSI, PS2 and APP) or bearing a risk factor polymorphism (ApoE) for Alzheimer's Disease were described. Second, the new type of proteases and mechanisms of regulation of cellular differentiation and development by processes of intramembrane...

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Identifiers

PMID: 17514900

Genes

APP

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