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Article

Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.

European archives of psychiatry and clinical neuroscience - 1 Jan 1999

Steiner H, Capell A, Leimer U, Haass C

Abstract excerpt

Alzheimer's disease is characterized by the invariable accumulation of senile plaques that are predominantly composed of amyloid beta-peptide (Abeta). Abeta is generated by proteolytic processing of the beta-amyloid precursor protein (betaAPP) involving the combined action of beta- and gamma-secr...

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PMID: 10653281
DOI: 10.1007/s004060050098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10653281-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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