Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation.

The Journal of biological chemistry - 13 Jul 2007

Watanabe Hiroki, Shionyu Masafumi, Kimura Tomoatsu, Kimata Koji, Watanabe Hideto

Abstract excerpt

Bone morphogenetic protein (BMP)-2/4 play critical roles in early embryogenesis and skeletal development. BMP-2/4 signals conduct into cells via two types of serine/threonine kinase receptors, known as BMPR-I (IA and IB) and BMPR-II. Here we identified splicing factor 3b subunit 4 (SF3b4) as a mo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Protein Receptors, Type I
Share to Bone Morphogenetic Protein Receptors, Type II
Share to Chondrogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Osteogenesis

Share to RNA Splicing Factors

Share to Smad Proteins

Share to Transforming Growth Factor beta

Share to Two-Hybrid System Techniques

Source

Identifiers

PMID: 17513295
DOI: 10.1074/jbc.M703292200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17513295-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation.PMID 17513295Read ↗

Heterozygous mutation of the splicing factor Sf3b4 affects development of the axial skeleton and forebrain in mouse.Semantic proximity Read ↗

Nuclear Export of Smads by RanBP3L Regulates Bone Morphogenetic Protein Signaling and Mesenchymal Stem Cell DifferentiationSemantic proximity Read ↗

Notch1 signaling regulates Sox9 and VEGFA expression and governs BMP2-induced endochondral ossification of mesenchymal stem cellsSemantic proximity Read ↗

14-3-3γ Knockdown Promotes Matrix Mineralization in human Mesenchymal Stromal CellsSemantic proximity Read ↗

BMP-2 promotes differentiation of osteoblasts and chondroblasts in Runx2-deficient cell lines.Semantic proximity Read ↗

Runx2 Is a Common Target of Transforming Growth Factor β1 and Bone Morphogenetic Protein 2, and Cooperation between Runx2 and Smad5 Induces Osteoblast-Specific Gene Expression in the Pluripotent Mesenchymal Precursor Cell Line C2C12Semantic proximity Read ↗

Runx3/AML2/Cbfa3 Regulates Early and Late Chondrocyte DifferentiationSemantic proximity Read ↗

Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiationSemantic proximity Read ↗

Molecular Mechanism of Runx2-Dependent Bone Development.Semantic proximity Read ↗

Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages.Semantic proximity Read ↗

Identification of Potential Modifiers of Runx2/Cbfa1 Activity in C2C12 Cells in Response to Bone Morphogenetic Protein-7Semantic proximity Read ↗

BMP-2/4 and BMP-6/7 Differentially Utilize Cell Surface Receptors to Induce Osteoblastic Differentiation of Human Bone Marrow-derived Mesenchymal Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.